0657 THE CIRCADIAN VARIANT OF IDIOPATHIC HYPERSOMNIA
نویسندگان
چکیده
منابع مشابه
Idiopathic hypersomnia
This article includes discussion of idiopathic hypersomnia (IH), which is characterized by excessive daytime sleepiness, difficulty awakening (sleep drunkenness), and undisturbed overnight sleep without cataplexy or known cause of excessive sleepiness. Excessive sleepiness (hypersomnolence) of unknown etiology, which cannot be explained by another disorder, would be considered idiopathic hypers...
متن کاملIdiopathic hypersomnia: a study of 77 cases.
STUDY OBJECTIVES To review the clinical and polysomnographic characteristics of idiopathic hypersomnia as well as the long-term response to treatment. SETTING The Respiratory Support and Sleep Centre at Papworth Hospital, Cambridge, UK. PATIENTS AND DESIGN A large database of more than 6000 patients with sleep disorders was reviewed. A retrospective study of the clinical and polysomnographi...
متن کاملIgG Abnormality in Narcolepsy and Idiopathic Hypersomnia
BACKGROUND A close association between narcolepsy and the Human Leukocyte Antigen (HLA)-DQB1*0602 allele suggests the involvement of the immune system, or possibly an autoimmune process. We investigated serum IgG levels in narcolepsy. METHODOLOGY/PRINCIPAL FINDINGS We measured the serum total IgG levels in 159 Japanese narcolepsy-cataplexy patients positive for the HLA-DQB1*0602 allele, 28 id...
متن کاملAltered Dynamics in the Circadian Oscillation of Clock Genes in Dermal Fibroblasts of Patients Suffering from Idiopathic Hypersomnia
From single cell organisms to the most complex life forms, the 24-hour circadian rhythm is important for numerous aspects of physiology and behavior such as daily periodic fluctuations in body temperature and sleep-wake cycles. Influenced by environmental cues - mainly by light input -, the central pacemaker in the thalamic suprachiasmatic nuclei (SCN) controls and regulates the internal clock ...
متن کاملSuccessful treatment of idiopathic hypersomnia and narcolepsy with modafinil.
1. Modafinil, a putative central alpha 1 adrenergic agonist, was tested in idiopathic hypersomnia and narcolepsy. 2. Sleep attacks and drowsiness were significantly decreased in 83% of 18 hypersomniac subjects and 71% of 24 narcoleptics. 3. When cataplectic episodes were not totally suppressed the association of a low dose of Clomipramine was successful in improving them. 4. Modafinil, used for...
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ژورنال
عنوان ژورنال: Sleep
سال: 2017
ISSN: 0161-8105,1550-9109
DOI: 10.1093/sleepj/zsx050.656